Chemistry Mianserin

(s)-mianserin.

mianserin tetracyclic piperazinoazepine; mirtazapine developed same team of organic chemists , differs via addition of nitrogen atom in 1 of rings. (s)-(+)-mianserin approximately 200–300 times more active enantiomer (r)-(−)-mianserin; hence, activity of mianserin lies in (s)-(+) isomer.